research – Psychedelic Frontier make the most of your dose Wed, 16 May 2018 11:00:06 +0000 en-US hourly 1 48719013 Michael Pollan Opens Up About His Powerful Psilocybin Trip on Stephen Colbert’s Late Show Wed, 16 May 2018 11:00:06 +0000 Michael Pollan Opens Up About His Powerful Psilocybin Trip on Stephen Colbert’s Late Show

It sure seems like psychedelics are finally going mainstream. Michael Pollan, the author of The Omnivore’s Dilemma and The Botany of Desire, turns his attention to psychedelic science and medicine in his latest book, How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence.

Pollan went on The Late Show to talk about tripping and the ego with Stephen Colbert. As an “immersion journalist,” Pollan decided to try LSD, psilocybin, and 5-MeO-DMT — a compound from the venom of the Sonoran desert toad — as research for his book. About his psilocybin trip, Pollan says:

I had this experience of ego dissolution. My sense of self fell apart. It was like a bunch of post-its being blown in the wind. And then I saw myself out on the landscape like paint.

Continue reading Michael Pollan Opens Up About His Powerful Psilocybin Trip on Stephen Colbert’s Late Show at Psychedelic Frontier.

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First Peek at My New Book ‘Magic Medicine’ Sun, 15 Apr 2018 13:00:35 +0000 First Peek at My New Book ‘Magic Medicine’

It’s finally here! Two years ago I started researching and writing Magic Medicine: A Trip Through the Intoxicating History and Modern-Day Use of Psychedelic Plants & Substances. After much tweaking and editing, the first printed copy is here! (The public release date is June 5th.)

From the very beginning, I wanted the book to more than just fascinating in its subject matter — I wanted it to be a beautiful object, something you would be proud to have on your nightstand or bookshelf. I wanted a book that would demand your attention and spark conversations, a book you could not help but pick up and thumb through, one that would make the perfect gift for that consciousness-curious person in your life.

I’m not exaggerating when I say I could not be happier with how the printed book came out! 

Continue reading First Peek at My New Book ‘Magic Medicine’ at Psychedelic Frontier.

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Coming Back to Life Wed, 07 Feb 2018 15:45:29 +0000 Coming Back to Life

This story by Rachel Kaplan first appeared in the MAPS Winter Bulletin 2017.

As I sit in a field of tall green grasses, feeling the earth beneath me and listening to the songs of meadowlarks, I am overwhelmed with gratitude for not only being alive but for finally wanting to be alive. I am overwhelmed with gratitude for often feeling a sense of peace in my self and feeling connected with myself, with others and the world. These are all new experiences for me that I never believed where possible until now, after being a participant in the MDMA-assisted psychotherapy study in Boulder.

This last year, after integrating the healing that happened in my MDMA-assisted psychotherapy sessions, has been a drastic contrast to the rest of my life. For the majority of my life I prayed to die and fought suicidal urges as I struggled with complex PTSD.

Continue reading Coming Back to Life at Psychedelic Frontier.

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Microdosing LSD: Smart Drug or Placebo? Tue, 14 Nov 2017 13:00:31 +0000 Microdosing LSD: Smart Drug or Placebo?

This guest post is by Marlene Rupp, whose fantastic writings and illustrations appear at

Microdosing LSD promises to act like a mix of Adderall and Prozac but without the side effects. Sounds too good to be true; is it? Some swear by microdosing while others call it a placebo effect. We researched the scientific explanations why microdosing might actually work, the risks involved and evaluated the evidence as of today. Here is what we found.

Microdosing gained currency in Silicon Valley in late 2015 and is spreading like wildfire across the rest of the world. Software developers microdose to enhance their problem-solving capabilities. Biohackers microdose to boost their productivity. People with mood disorders microdose to alleviate symptoms of depression and anxiety.

Stories of young professionals taking tiny doses of acid before going to the office have been making headlines all throughout the media with The New York Times, The Guardian, BBC, CNN, Forbes, Wired, Rolling Stone and Vice picking up on the trend.

Continue reading Microdosing LSD: Smart Drug or Placebo? at Psychedelic Frontier.

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James Fadiman Discusses the Many Benefits of Microdosing Thu, 26 Oct 2017 11:02:59 +0000 James Fadiman Discusses the Many Benefits of Microdosing

Altered Conference (3-4 November, 2017 in Berlin) is an international gathering of consciousness explorers from all backgrounds to take part in talks, workshops and rituals on the subject of psychedelics, conscious practices, and social issues facilitated by leading experts and researchers. Interested in attending? Use code PSYCHEDELICFRONTIER which is good for a 20% discount.

At the conference, Dr. James Fadiman & Dr. Sophia Korb will provide a talk called about their microdosing research project, which has enrolled over a thousand subjects around the world. I caught up with Dr. Fadiman — a leading psychedelic researcher and author of the popular trip guide, The Psychedelic Explorer’s Guide — about his microdosing research, the future of psychedelics, and the themes of the upcoming conference.

Hi James, and welcome to the Psychedelic Frontier! Your upcoming talk at Altered Conference (in Berlin, 3-4 November 2017) looks absolutely fascinating.

Continue reading James Fadiman Discusses the Many Benefits of Microdosing at Psychedelic Frontier.

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Video: Can Ketamine Help You Reduce Problem Drinking? Tue, 19 Sep 2017 11:00:08 +0000 Video: Can Ketamine Help You Reduce Problem Drinking?

In this episode of Vice Video’s High Society series, a young man embarks on a full-blown ketamine trip in the hopes of reducing his compulsive drinking habit. It’s part of a controlled study led by Dr. Ravi Das, a psychopharmacologist at University College London, to examine whether ketamine can weaken certain memory connections — and thereby loosen the grip of addictive substances over people’s minds.

From the Vice Video description:

Timmy Davis is not an alcoholic. But like many twenty-something students, he’s worried he may be drinking too much.

Timmy has volunteered for Dr. Das’ latest experiment, in which 90 volunteers will receive a ketamine infusion in a controlled setting. Timmy is no stranger to psychedelics. But could a drug he has previously encountered recreationally really help him cut down his drinking?

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Continue reading Video: Can Ketamine Help You Reduce Problem Drinking? at Psychedelic Frontier.

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Scientists Unlock the Mystery of Magic Mushrooms, Allowing for Mass Production of Psilocybin Sat, 19 Aug 2017 11:00:30 +0000 Scientists Unlock the Mystery of Magic Mushrooms, Allowing for Mass Production of Psilocybin

Some sixty years ago, Albert Hofmann — the Swiss chemist better known for discovering LSD — first isolated the active components of “magic” mushrooms, psilocybin and psilocin. Yet the question of how, exactly, the mushrooms produced these unique compounds remained a mystery ever since.

Until now, that is. Scientists at Friedrich Schiller University Jena in Germany have identified the four key enzymes used by these fungal bio-factories to produce their magical ingredients. To accomplish this, Dr. Dirk Hoffmeister and his team sequenced the entire genome of two psilocybin mushroom species, Psilocybe cubensis and Psilocybe cyanescens.

Even more impressive, they were able to splice the mushroom genes into E. coli bacteria so that they, too, could produce psilocybin.

The upshot? A remarkably effective “one-pot reaction” which takes a serotonin-like compound called 4-hydroxy-L-tryptophan and pumps out psilocybin.

The new method improves greatly upon the efficiency of the tried-and-true method of growing mushrooms, and lays the groundwork for industrial-scale psilocybin production.  

Continue reading Scientists Unlock the Mystery of Magic Mushrooms, Allowing for Mass Production of Psilocybin at Psychedelic Frontier.

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Religious Leaders Tripping on Magic Mushrooms for Science Tue, 11 Jul 2017 11:00:55 +0000 Religious Leaders Tripping on Magic Mushrooms for Science

Among traditional cultures, psychedelic plants and fungi have long been viewed as spiritual medicines. Indeed, why partake of sacraments such as mushrooms, ayahuasca, or peyote cacti if not for their spiritual power? Yet in the West, where “spirituality” has long been conflated with religion — and where few sacraments aside from communion wafers and a bit of wine are acknowledged — these visionary plants have been viewed with suspicion.

That’s all changing. Among progressive scientists, psychedelics are now all the rage. Psilocybin, the active component of “magic” mushrooms, has shown promise in pilot studies for a wide range of applications, including quitting smoking and relieving anxiety among terminal cancer patients.

So in the midst of a “Psychedelic Renaissance,” it’s only fitting that researchers would turn their attention to the spiritual dimension of psychedelics. At Johns Hopkins University, 24 spiritual leaders — including Catholic priests, Protestant pastors, rabbis, and even a Zen Buddhist — are being dosed with psilocybin.

Continue reading Religious Leaders Tripping on Magic Mushrooms for Science at Psychedelic Frontier.

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Why Dr. Bronner’s Soaps Is Donating $5 Million to MAPS Tue, 06 Jun 2017 11:00:09 +0000 Why Dr. Bronner’s Soaps Is Donating $5 Million to MAPS

This essay by David Bronner, CEO of Dr. Bronner’s and Board Member of the Multidisciplinary Association for Psychedelic Studies, was first published in the MAPS Bulletin and on

Our family company, Dr. Bronner’s, donates a lot of resources to social justice NGOs and campaigns, including over $1 million to various state-level cannabis legalization campaigns in 2016. Collectively, well north of $40 million was raised in the 2016 election cycle alone to end prohibition and stop the enormous waste of taxpayer and law enforcement resources from ruining the lives of upstanding citizens and their families. Even with the Trump administration, momentum is growing to recognize medical cannabis at the federal level and remove it from Schedule 1 of the Controlled Substances Act. Now, we have the opportunity to legalize MDMA as a U.S. Food and Drug Administration (FDA)-approved medicine, to be available in all 50 states, for a total cost that is substantially less than what we as a movement are investing into legalizing medical and recreational cannabis.

Continue reading Why Dr. Bronner’s Soaps Is Donating $5 Million to MAPS at Psychedelic Frontier.

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The Walls Come Tumbling Down Tue, 16 May 2017 11:00:54 +0000 The Walls Come Tumbling Down

This story by Andy Gold first appeared in the MAPS Bulletin, Winter 2016 edition.

I went for my first MDMA-assisted psychotherapy session on November 30, 2015, the Monday after Thanksgiving. Was it really a coincidence that the colonoscopy which found a malignant tumor in my colon some years earlier had also taken place on the Monday after Thanksgiving? I think not. Full circle, indeed.

I arrived at the site in Marin County, Calif., where the session was to take place, at 9:30 in the morning. One of the study requirements is that you do the sessions while fasting. Someone also has to bring you to the site and pick you up. My adult son dropped me off and took a couple of minutes to meet Dr. Phil Wolfson and Julane Andries (the study co-therapists) and see their place. I think he was suitably impressed by the location, and comfortable with the idea of his father tripping in that environment, under the care of those people.

Continue reading The Walls Come Tumbling Down at Psychedelic Frontier.

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