fear – Psychedelic Frontier http://psychedelicfrontier.com make the most of your dose Wed, 16 May 2018 11:00:06 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.5 48719013 Control Freaks: America and its Uncontrolled Substances http://psychedelicfrontier.com/control-freaks-america-uncontrolled-substances/ http://psychedelicfrontier.com/control-freaks-america-uncontrolled-substances/#comments Tue, 26 Nov 2013 18:38:36 +0000 http://psychedelicfrontier.com/?p=1741 Control Freaks: America and its Uncontrolled Substances

I’ve analyzed the psychology of Prohibition before, concluding that the War on Drugs is a deceit maintained by the national ego. In this article I take a deeper look at how the desire for control affects our laws and language. This is a prelude to my six-part essay on language called Reclaiming the Prohibition Debate.

None are more hopelessly enslaved than those who falsely believe they are free.  

—Goethe

Humans like to feel in control. This is not always a bad thing, but it becomes problematic when we are so obsessed with the illusion of control that we forego the real thing.

The war on drugs is a lost war, and worse, a sham intended to placate us. This desperate bid to maintain the appearance of law and order does not benefit us; it benefits the prison-industrial complex (now a lucrative private business, about as anti-humanitarian as a business can get), police departments (who use the War on Drugs to seize property and justify their bloated budgets), pharmaceutical companies (who oppose public access to cheap, effective, and un-patentable chemicals), and of course drug cartels.

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Ego, Fear, and the War on Drug Users http://psychedelicfrontier.com/ego-fear-war-drug-users/ http://psychedelicfrontier.com/ego-fear-war-drug-users/#comments Mon, 10 Jun 2013 21:48:34 +0000 http://www.psychedelicfrontier.com/?p=778 Ego, Fear, and the War on Drug Users

“Over one’s mind and over one’s body, the individual is sovereign.”

—John Stuart Mill

From the point of view of psychedelic enthusiasts, the prohibitionist stance is farcically weak. The moral imperative could not be more obvious: stop jailing non-violent consciousness explorers and give us back our tax dollars.

But let’s consider how we got here to begin with. I don’t want to talk about Nixon and the Controlled Substance Act, or the DEA, or how America has exported its neurotic drug policy to the rest of the world. I won’t even present data revealing how ineffective and dehumanizing the War on Some Drug Users really is. That’s all been covered before.

Today, I want to examine the psychology of a culture that gives lip service to human rights, yet imprisons people for experiencing unsanctioned forms of consciousness. Why would we cage our brothers and sisters this way?

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Low dose psychedelics increase neurogenesis, help mice unlearn fear http://psychedelicfrontier.com/low-dose-psychedelics-increase-neurogenesis-help-mice-unlearn-fear/ http://psychedelicfrontier.com/low-dose-psychedelics-increase-neurogenesis-help-mice-unlearn-fear/#comments Thu, 06 Jun 2013 15:57:13 +0000 http://psychedelicfrontier.com/?p=869 Low dose psychedelics increase neurogenesis, help mice unlearn fear

A new study of mice published in Experimental Brain Research shows that low doses (but not high doses) of psychedelics increase the rate of neuron creation in the hippocampus, and help the mice to rapidly unlearn conditioned fear responses.

From the abstract (paragraph breaks added for readability):

Drugs that modulate serotonin (5-HT) synaptic concentrations impact neurogenesis and hippocampal (HPC)-dependent learning. The primary objective is to determine the extent to which psilocybin (PSOP) modulates neurogenesis and thereby affects acquisition and extinction of HPC-dependent trace fear conditioning.

PSOP, the 5-HT2A agonist 25I-NBMeO and the 5-HT2A/Cantagonist ketanserin were administered via an acute intraperitoneal injection to mice. Trace fear conditioning was measured as the amount of time spent immobile in the presence of the conditioned stimulus (CS, auditory tone), trace (silent interval) and post-trace interval over 10 trials. Extinction was determined by the number of trials required to resume mobility during CS, trace and post-trace when the shock was not delivered.

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Ketamine shows promise in treating “Fear of Harm” http://psychedelicfrontier.com/ketamine-shows-promise-in-treating-fear-of-harm/ http://psychedelicfrontier.com/ketamine-shows-promise-in-treating-fear-of-harm/#respond Mon, 25 Mar 2013 21:03:03 +0000 http://www.psychedelicfrontier.com/?p=175 Ketamine shows promise in treating “Fear of Harm”

There has been a huge resurgence of research on psychedelic and dissociative drugs recently. This is very promising because for 40 years, the study of these very promising medical compounds was shelved in the name of prohibition. Finally, after decades of hiatus, we are able to shed light on some of these compounds in controlled clinical settings. The studies may be small and few in number right now, but their positive results should help open the door to larger and ever more diverse studies. If early studies are any indication, the medical potential of psychedelics is absolutely vast.

What a relief to see these long-outcast compounds invited back to the fold of mainstream science. New and pioneering studies of psilocybin, MDMA, LSD, ketamine, and others are playing a huge role in renewing the good name of all these compounds in the public eye. Substances like these have offered powerful benefits to humanity for centuries, so it’s about time modern society starting taking them seriously instead of treating them like toxic poisons. 

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